Oral cancer chemoprevention: COX-2 inhibitor a covenant
نویسندگان
چکیده
منابع مشابه
A Discussion on Chemoprevention of Oral Cancer by Selective Cyclooxygenase-2 (cox-2) Inhibitors
A. K. SINGH, A. PANDEY, M. TEWARI, KUMAR PRAKASH, H. S. SHUKLA, H. P. PANDEY Department of Biochemistry, Faculty of Science, Banaras Hindu University, Varanasi, India Department of Surgical Oncology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India Department of Biotechnology, IBMER, Mangalayatan University, Aligarh, India Department of Statistics, Faculty of Science, Ba...
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Evidence derived from several lines of investigation suggest that prostaglandins, metabolites of arachidonic acid, play an important role in colon cancer development. Elevated prostaglandin levels are found in colon cancers and their precursor lesions, adenomatous polyps. Agents such as aspirin and NSAIDs, which inhibit the generation of these arachidonic acid metabolites, are associated with a...
متن کاملChemoprevention of Oral Cancer
Oral cancer is one among the ten most common cancers in the world and shows a marked geographic variation in occurrence. It causes considerable morbidity and is associated with a 5-year survival rate of less than 50%. Current treatment primarily consists of surgery and radiotherapy and improvement in longterm cure rates with these modalities has reached a plateau. As, curative therapy available...
متن کاملOral Cancer and Chemoprevention
Oral cancer is one of the major global threats to public health. The development of oral cancer is a tobacco-related multistep and multifocal process involving field cancerization and carcinogenesis. As, curative therapy available for oral cancer often results in debilitating changes in appearance, speech, swallowing and breathing, preventive strategies are desirable. Chemoprevention , is the u...
متن کاملA mechanism for cox-2 inhibitor anti-inflammatory activity in chemoprevention of epithelial cancers.
Epidemiological and experimental data support the use of nonsteroidal anti-inflammatory drugs, including specific inhibitors of cyclooxygenase 2 (Cox-2), as chemopreventive agents in a number of epithelial cancers, including colon, mammary, esophageal, lung, and oral cavity (1). There is also evidence to suggest that nonsteroidal anti-inflammatory drugs may be chemopreventive against ovarian ca...
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ژورنال
عنوان ژورنال: International Journal of Scientific Reports
سال: 2021
ISSN: 2454-2164,2454-2156
DOI: 10.18203/issn.2454-2156.intjscirep20211043